What condition does tadalafil primarily address?

Tadalafil primarily addresses erectile dysfunction, a condition in which a man has difficulty achieving or maintaining an erection sufficient for sexual activity. Tadalafil works by increasing blood flow to the penis during sexual stimulation by inhibiting the phosphodiesterase type 5 (PDE5) enzyme, which leads to enhanced erection quality.

While tadalafil is sometimes used to treat pulmonary arterial hypertension as an off-label use, its primary and most widely recognized indication is for erectile dysfunction. The other conditions listed, such as depression and diabetes, do not fall under the therapeutic indications for tadalafil, as this drug specifically targets the physiological mechanisms involved in erectile function rather than mental health or metabolic disorders.