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A tablet designed to not dissolve until it reaches the small intestine utilizes an enteric coating. This coating is specifically formulated to withstand the acidic environment of the stomach, preventing the tablet from breaking down prematurely. As a result, the active ingredients are protected from degradation in the stomach and are only released in the small intestine, where the pH is more favorable for dissolution.
Enteric coatings can improve the bioavailability of certain medications, especially those that are sensitive to stomach acid, and also help minimize gastrointestinal irritation. This mechanism is distinct from sustained or controlled release formulations, which are designed to release their active ingredients gradually over time but do not specifically target the small intestine as a site for dissolution. Capsules, while also a common dosage form, do not inherently possess the same protective coating characteristics that allow for delayed dissolution in the small intestine.