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Accupril belongs to the class of drugs known as ACE inhibitors. ACE, or angiotensin-converting enzyme, inhibitors work by blocking the action of the enzyme that converts angiotensin I to angiotensin II, a potent vasoconstrictor. This helps to lower blood pressure by causing blood vessels to relax and widen, which improves blood flow and reduces the workload on the heart.

The role of ACE inhibitors like Accupril is particularly important in the treatment of conditions such as hypertension (high blood pressure) and heart failure, as they can improve outcomes and reduce the risk of complications. By reducing the production of angiotensin II, these medications can also help to decrease the secretion of aldosterone, leading to reduced sodium and water retention in the body.

Other classes of drugs listed do not share this mechanism. Beta blockers, for instance, work by blocking the effects of adrenaline on beta receptors, resulting in decreased heart rate and force of contraction. Calcium channel blockers prevent calcium from entering cells of the heart and blood vessel walls, leading to decreased heart contractility and vasodilation. Antidepressants are primarily aimed at treating mood disorders and have different mechanisms of action related to neurotransmitters in the brain rather than blood pressure regulation

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