What is the maximum volume that can be injected intradermally?

The maximum volume that can be injected intradermally is 0.1 mL. This is primarily due to the structure and function of the dermal layer of the skin. The intradermal injection technique involves delivering medication into the dermis, which is a relatively thin layer compared to other tissues. The limited volume, 0.1 mL, ensures that the medication can be properly absorbed and minimizes the risk of tissue damage or discomfort.

When larger volumes are injected, there is a higher risk of leakage and inadequate absorption, which can lead to complications such as abscesses or inflammatory reactions. Given these considerations, 0.1 mL is regarded as the maximum safe volume for intradermal injections, especially for purposes like allergy testing or vaccinations.