What is the method by which drugs are typically removed from the body?

The primary method by which drugs are eliminated from the body is through urine. The kidneys play a crucial role in this process by filtering the blood and excreting waste products, including metabolites of medications, into the urine. This route is significant because it facilitates the removal of substances that the body does not need, thus helping to maintain homeostasis and prevent toxicity.

While other methods, such as through sweat, feces, and respiration, can contribute to the elimination of certain drugs or their metabolites, they are not the primary pathways. For instance, drugs can be excreted in sweat and feces, but these amounts are generally much smaller compared to what is eliminated via urine. Respiration is also involved in eliminating volatile substances, but again, this is not the main route for most drugs. In summary, the renal system's ability to remove drugs effectively makes urine the most significant medium for drug excretion.