What is the primary indication for Spironolactone?

Spironolactone is primarily indicated for the treatment of edema and hypertension. It is a diuretic that works by inhibiting the action of aldosterone, a hormone that promotes sodium retention and potassium excretion in the kidneys. By blocking aldosterone, spironolactone helps the body retain potassium while promoting the excretion of sodium and water, which can result in reduced fluid retention (edema) in conditions such as heart failure, liver cirrhosis, or nephrotic syndrome, as well as lowering blood pressure in individuals with hypertension.

The other options pertain to different medical conditions that are not treated with spironolactone. Anxiety disorders, depression, and schizophrenia are primarily addressed with mental health medications, not diuretics. Thus, spironolactone's specific role in managing fluid balance and blood pressure underscores its importance in these related conditions.