What method is used to ensure equal distribution of ingredients in compounding?

Geometric dilution is the method used to ensure equal distribution of ingredients in compounding, particularly when one ingredient is present in a smaller quantity compared to the other components. This technique involves mixing the smaller quantity of the ingredient with an equal amount of the larger quantity of diluent, creating a homogeneous mixture. This process is then repeated, progressively incorporating more of the larger bulk ingredient until the desired total amount is achieved.

By doing this, each molecule of the potent ingredient is evenly distributed throughout the entire mixture, which is crucial for consistency in dosage when preparing compounded medications. This method is especially important in pharmacy settings, where the precision of active ingredients is vital for patient safety and efficacy of the compounded product.