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Lotrel is classified as an antihypertensive medication that contains a combination of a calcium channel blocker and an ACE inhibitor. The calcium channel blocker component works by relaxing the blood vessels, which helps to lower blood pressure, while the ACE inhibitor component further contributes to blood pressure reduction by preventing the conversion of angiotensin I to angiotensin II, a substance that narrows blood vessels.

Understanding the classification of Lotrel is significant for recognizing its role in managing hypertension. This combination therapy is effective in improving cardiovascular outcomes by addressing blood pressure from multiple physiological mechanisms. The use of both a calcium channel blocker and an ACE inhibitor can enhance the overall efficacy of treatment compared to using either agent alone, making it a common choice in the management of high blood pressure.

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