What type of drugs require a prescription to be dispensed?

Legend drugs are those that require a prescription to be dispensed due to their potential risks, side effects, and the need for professional guidance in their use. The term "legend" refers to the label on the medication that includes a warning stating that it should not be dispensed without a prescription. These drugs typically address a variety of health conditions, and the involvement of a healthcare provider ensures that patients receive the appropriate dosage and monitoring for their specific medical needs.

While controlled substances also require a prescription, they fall under a more specific regulatory category due to their potential for abuse and dependence. Investigational drugs are often in clinical trials and also require a prescription, but they do not have the same regulatory status as legend drugs which are established in the market. Over-the-counter (OTC) drugs do not require a prescription, as they are considered safe for use without professional oversight for common ailments. Thus, legend drugs are categorized specifically as those that necessitate a prescription before they can be dispensed to patients.