Which drug is an antihipertensive that is a combination of an ACE inhibitor and diuretic?

The selected answer is indeed the correct choice. Prinizide is a medication that combines an ACE inhibitor (lisinopril) with a diuretic (hydrochlorothiazide). This combination works synergistically to lower blood pressure. The ACE inhibitor helps to relax blood vessels by inhibiting the angiotensin-converting enzyme, while the diuretic aids in reducing blood volume by promoting the excretion of sodium and water. This dual approach is effective in managing hypertension by addressing both fluid retention and vascular resistance.

Other options represent different classes of medications unrelated to hypertension management in the same manner. Crestor, for instance, is a statin used for lowering cholesterol, while Tricor is primarily used to reduce triglyceride levels. Effexor, on the other hand, is an antidepressant that works on serotonin and norepinephrine reuptake inhibition and has no direct effect on blood pressure or hypertension treatment. Thus, the unique combination of an ACE inhibitor and a diuretic in Prinizide clearly establishes its role as an antihypertensive agent.