Which of the following medications is considered controlled?

Morphine Sulfate is classified as a controlled medication due to its high potential for abuse, dependence, and addiction. It is an opioid analgesic, which means it is primarily used for the management of moderate to severe pain. Due to its potency and effect on the central nervous system, morphine is regulated under the Controlled Substances Act, which categorizes it into Schedule II. This classification restricts its prescription and distribution to ensure safe use, while also providing measures for monitoring due to the risks associated with its use.

In contrast, the other options listed are not classified as controlled substances. Rosuvastatin Calcium is primarily used to lower cholesterol and is not associated with abuse potential. Prednisone is a corticosteroid used to treat inflammatory conditions and has different regulatory controls. Clonidine Hydrochloride, while it can have sedative effects and is used in hypertension management, does not carry the same level of risk for abuse as opioids like morphine.