Which vitamin’s deficiency can lead to neurological issues due to its role in energy metabolism?

Vitamin B1, also known as thiamine, is essential for energy metabolism, particularly in the conversion of carbohydrates into energy within the body. It plays a crucial role in the functioning of neurons, as it is involved in several biochemical pathways that produce energy for nerve cells. A deficiency in thiamine can lead to a range of neurological problems, including Wernicke-Korsakoff syndrome, which is characterized by confusion, memory loss, and coordination issues.

In contrast, the other vitamins listed have different primary roles in the body. Vitamin A is important for vision and immune function, Vitamin K is primarily involved in blood clotting, and Vitamin D is mainly associated with bone health and calcium metabolism. None of these vitamins have the same direct impact on energy metabolism in the nervous system as Vitamin B1 does, which is why a deficiency in thiamine specifically can lead to neurological issues.